Diterpenoids from the Hainan Soft Coral Sinularia parva
Li, Y; Gao, AH; Huang, H; Li, J; Mollo, E; Gavagnin, M; Cimino, G; Gu, YC; Guo, YW; ywguo@mail.shcnc.ac.cn
2009
发表期刊HELVETICA CHIMICA ACTA
ISSN0018-019X
卷号92期号:7页码:1341-1348
摘要Two new cembrane diterpenes, sinulaparvalides A and B (1 and 2, resp.), which contain an intriguing seven-membered lactone moiety, along with the four known related cembranoids 3-6, were isolated from the Hainan soft coral Sinularia parva. The structures of compounds I and 2 were established by spectroscopic methods, mainly on the basis of 2D-NMR techniques, and were confirmed by single-crystal X-ray diffraction analysis. The in vitro cytotoxic activities of these compounds were tested on human colon carcinoma (HCT-116), human promyelocytic leukemia (HL-60), and human lung carcinoma (A-549) tumor cell lines.
部门归属[Li, Yan; Gao, An-Hui; Li, Jia; Guo, Yue-Wei] Chinese Acad Sci, Shanghai Inst Mat Med, State Key Lab Drug Res, Shanghai 201203, Peoples R China; [Huang, Hui] Chinese Acad Sci, S China Sea Inst Oceanol, Guangzhou 510301, Guangdong, Peoples R China; [Mollo, Ernesto; Gavagnin, Margherita; Cimino, Guido] CNR, Ist Chim Biomol, I-80078 Naples, Italy; [Gu, Yu-Cheng] Syngenta, Jealotts Hill Int Res Ctr, Bracknell RG42 6EY, Berks, England
学科领域Chemistry, Multidisciplinary
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收录类别sci
资助项目LMB
WOS记录号WOS:000268622500013
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文献类型期刊论文
条目标识符http://ir.scsio.ac.cn/handle/344004/5090
专题中科院海洋生物资源可持续利用重点实验室
通讯作者ywguo@mail.shcnc.ac.cn
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GB/T 7714
Li, Y,Gao, AH,Huang, H,et al. Diterpenoids from the Hainan Soft Coral Sinularia parva[J]. HELVETICA CHIMICA ACTA,2009,92(7):1341-1348.
APA Li, Y.,Gao, AH.,Huang, H.,Li, J.,Mollo, E.,...&ywguo@mail.shcnc.ac.cn.(2009).Diterpenoids from the Hainan Soft Coral Sinularia parva.HELVETICA CHIMICA ACTA,92(7),1341-1348.
MLA Li, Y,et al."Diterpenoids from the Hainan Soft Coral Sinularia parva".HELVETICA CHIMICA ACTA 92.7(2009):1341-1348.
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