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学科主题: Chemistry, Multidisciplinary
题名: Diterpenoids from the Hainan Soft Coral Sinularia parva
作者: Li, Y ; Gao, AH ; Huang, H ; Li, J ; Mollo, E ; Gavagnin, M ; Cimino, G ; Gu, YC ; Guo, YW
通讯作者: ywguo@mail.shcnc.ac.cn
刊名: HELVETICA CHIMICA ACTA
发表日期: 2009
卷: 92, 期:7, 页:1341-1348
收录类别: sci
部门归属: [Li, Yan; Gao, An-Hui; Li, Jia; Guo, Yue-Wei] Chinese Acad Sci, Shanghai Inst Mat Med, State Key Lab Drug Res, Shanghai 201203, Peoples R China; [Huang, Hui] Chinese Acad Sci, S China Sea Inst Oceanol, Guangzhou 510301, Guangdong, Peoples R China; [Mollo, Ernesto; Gavagnin, Margherita; Cimino, Guido] CNR, Ist Chim Biomol, I-80078 Naples, Italy; [Gu, Yu-Cheng] Syngenta, Jealotts Hill Int Res Ctr, Bracknell RG42 6EY, Berks, England
项目归属: LMB
摘要: Two new cembrane diterpenes, sinulaparvalides A and B (1 and 2, resp.), which contain an intriguing seven-membered lactone moiety, along with the four known related cembranoids 3-6, were isolated from the Hainan soft coral Sinularia parva. The structures of compounds I and 2 were established by spectroscopic methods, mainly on the basis of 2D-NMR techniques, and were confirmed by single-crystal X-ray diffraction analysis. The in vitro cytotoxic activities of these compounds were tested on human colon carcinoma (HCT-116), human promyelocytic leukemia (HL-60), and human lung carcinoma (A-549) tumor cell lines.
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WOS记录号: WOS:000268622500013
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内容类型: 期刊论文
URI标识: http://ir.scsio.ac.cn/handle/344004/5090
Appears in Collections:中科院海洋生物资源可持续利用重点实验室_期刊论文

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Li, Y; Gao, AH; Huang, H; Li, J; Mollo, E; Gavagnin, M; Cimino, G; Gu, YC; Guo, YW.Diterpenoids from the Hainan Soft Coral Sinularia parva,HELVETICA CHIMICA ACTA,2009,92(7):1341-1348
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