Chromones from the Endophytic Fungus Pestalotiopsis sp Isolated from the Chinese Mangrove Plant Rhizophora mucronata
Xu, J; Kjer, J; Sendker, J; Wray, V; Guan, HS; Edrada, R; Lin, WH; Wu, J; Proksch, P; wwujun2003@yahoo.com; proksch@uni-duesseldorf.de
2009
发表期刊JOURNAL OF NATURAL PRODUCTS
ISSN0163-3864
卷号72期号:4页码:662-665
摘要Six new chromones, named pestalotiopsones A-F (1-6), and the known derivative 7-hydroxy-2-(2-hydroxypropyl)-5-methylchromone (7) were obtained from the mycelia and culture filtrate of the mangrove endophytic fungus Pestalotiopsis sp., which was isolated from leaves of the Chinese Mangrove plant Rhizophora mucronata. Their structures were elucidated on the basis of spectroscopic data. Pestalotiopsones A-F are chromones having both an alkyl side chain substituted at C-2 and a free or substituted carboxyl group at C-5. Compound 6 exhibited moderate cytotoxicity against the murine cancer cell line L5178Y, whereas the other investigated compounds proved to be inactive.
部门归属[Xu, Jing; Kjer, Julia; Sendker, Jandirk; Proksch, Peter] Univ Dusseldorf, Inst Pharmazeut Biol & Biotechnol, D-40225 Dusseldorf, Germany; [Xu, Jing; Guan, Huashi] Ocean Univ China, Chinese Minist Educ, Inst Marine Drugs & Food, Key Lab Marine Drugs, Qingdao 266003, Peoples R China; [Wray, Victor] Helmholtz Ctr Infect Res, Dept Biol Struct, D-38124 Braunschweig, Germany; [Wu, Jun] Chinese Acad Sci, Key Lab Marine Bioresources Sustainable Utilizat, S China Sea Inst Oceanol, Guangzhou 510301, Guangdong, Peoples R China; [Edrada, RuAngelie] Univ Strathclyde, Strathclyde Inst Pharm & Biomed Sci, Glasgow G4 0NR, Lanark, Scotland; [Lin, Wenhan] Peking Univ, Natl Res Labs Nat & Biomimet Drugs, Hlth Sci Ctr, Beijing 100083, Peoples R China
学科领域Plant Sciences ; Chemistry, Medicinal ; Pharmacology & Pharmacy
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收录类别sci
资助项目LMB
WOS记录号WOS:000265530000011
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被引频次:74[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.scsio.ac.cn/handle/344004/5118
专题中科院海洋生物资源可持续利用重点实验室
通讯作者wwujun2003@yahoo.com; proksch@uni-duesseldorf.de
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Xu, J,Kjer, J,Sendker, J,et al. Chromones from the Endophytic Fungus Pestalotiopsis sp Isolated from the Chinese Mangrove Plant Rhizophora mucronata[J]. JOURNAL OF NATURAL PRODUCTS,2009,72(4):662-665.
APA Xu, J.,Kjer, J.,Sendker, J.,Wray, V.,Guan, HS.,...&proksch@uni-duesseldorf.de.(2009).Chromones from the Endophytic Fungus Pestalotiopsis sp Isolated from the Chinese Mangrove Plant Rhizophora mucronata.JOURNAL OF NATURAL PRODUCTS,72(4),662-665.
MLA Xu, J,et al."Chromones from the Endophytic Fungus Pestalotiopsis sp Isolated from the Chinese Mangrove Plant Rhizophora mucronata".JOURNAL OF NATURAL PRODUCTS 72.4(2009):662-665.
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