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学科主题: Plant Sciences; Chemistry, Medicinal; Pharmacology & Pharmacy
题名: Chromones from the Endophytic Fungus Pestalotiopsis sp Isolated from the Chinese Mangrove Plant Rhizophora mucronata
作者: Xu, J ; Kjer, J ; Sendker, J ; Wray, V ; Guan, HS ; Edrada, R ; Lin, WH ; Wu, J ; Proksch, P
通讯作者: wwujun2003@yahoo.com ; proksch@uni-duesseldorf.de
刊名: JOURNAL OF NATURAL PRODUCTS
发表日期: 2009
卷: 72, 期:4, 页:662-665
收录类别: sci
部门归属: [Xu, Jing; Kjer, Julia; Sendker, Jandirk; Proksch, Peter] Univ Dusseldorf, Inst Pharmazeut Biol & Biotechnol, D-40225 Dusseldorf, Germany; [Xu, Jing; Guan, Huashi] Ocean Univ China, Chinese Minist Educ, Inst Marine Drugs & Food, Key Lab Marine Drugs, Qingdao 266003, Peoples R China; [Wray, Victor] Helmholtz Ctr Infect Res, Dept Biol Struct, D-38124 Braunschweig, Germany; [Wu, Jun] Chinese Acad Sci, Key Lab Marine Bioresources Sustainable Utilizat, S China Sea Inst Oceanol, Guangzhou 510301, Guangdong, Peoples R China; [Edrada, RuAngelie] Univ Strathclyde, Strathclyde Inst Pharm & Biomed Sci, Glasgow G4 0NR, Lanark, Scotland; [Lin, Wenhan] Peking Univ, Natl Res Labs Nat & Biomimet Drugs, Hlth Sci Ctr, Beijing 100083, Peoples R China
项目归属: LMB
摘要: Six new chromones, named pestalotiopsones A-F (1-6), and the known derivative 7-hydroxy-2-(2-hydroxypropyl)-5-methylchromone (7) were obtained from the mycelia and culture filtrate of the mangrove endophytic fungus Pestalotiopsis sp., which was isolated from leaves of the Chinese Mangrove plant Rhizophora mucronata. Their structures were elucidated on the basis of spectroscopic data. Pestalotiopsones A-F are chromones having both an alkyl side chain substituted at C-2 and a free or substituted carboxyl group at C-5. Compound 6 exhibited moderate cytotoxicity against the murine cancer cell line L5178Y, whereas the other investigated compounds proved to be inactive.
原文出处: 查看原文
WOS记录号: WOS:000265530000011
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内容类型: 期刊论文
URI标识: http://ir.scsio.ac.cn/handle/344004/5118
Appears in Collections:中科院海洋生物资源可持续利用重点实验室_期刊论文

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Recommended Citation:
Xu, J; Kjer, J; Sendker, J; Wray, V; Guan, HS; Edrada, R; Lin, WH; Wu, J; Proksch, P.Chromones from the Endophytic Fungus Pestalotiopsis sp Isolated from the Chinese Mangrove Plant Rhizophora mucronata,JOURNAL OF NATURAL PRODUCTS,2009,72(4):662-665
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文件名: Chromones from the Endophytic Fungus Pestalotiopsis sp Isolated from the Chinese Mangrove Plant Rhizophora mucronata .pdf
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