Tarennanosides A-H, Eight New Lignan Glucosides from Tarenna attenuata and Their Protective Effect on H2O2-Induced Impairment in PC12 Cells
Yang, XW; He, HP; Du, ZZ; Liu, HY; Di, YT; Ma, YL; Wang, F; Lin, H; Zuo, YQ; Li, L; Hao, XJ; haoxj@mail.kib.ac.cn
2009
发表期刊CHEMISTRY & BIODIVERSITY
ISSN1612-1872
卷号6期号:4页码:540-550
摘要Eight new lignan glucosides, tarennanosides A-H (1-8, resp.), were isolated from the whole plant of Tarenna attenuata, together with three known compounds, fernandoside, (-)-lyoniresinol, and (-)isolariciresinol. The planar structures of new compounds were elucidated mainly by analysis of physical and spectroscopic data, and the absolute configurations were determined by acid hydrolysis as well as CD spectroscopy. Compounds I and 2 exhibited potent antioxidant activities against H2O2-induced impairment in PC12 cells. Preliminary mechanism study by the 1,1-diphenyl-2-picrylhydrazyl (DPPH) method showed that these two compounds could act as radical scavengers.
部门归属[Yang, Xian-Wen; He, Hong-Ping; Du, Zhi-Zhi; Liu, Hai-Yang; Di, Ying-Tong; Hao, Xiao-Jiang] Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources W China, Kunming 650204, Peoples R China; [Yang, Xian-Wen] Chinese Acad Sci, S China Sea Inst Oceanol, Key Lab Marine Bioresources Sustainable Utilizat, Guangzhou 510301, Guangdong, Peoples R China; [Ma, Yan-Lin; Wang, Fang; Lin, Hua; Zuo, Yi-Qing; Li, Ling] Kunming Med Coll, Yunnan Pharmacol Labs Nat Prod, Kunming 650031, Peoples R China
学科领域Biochemistry & Molecular Biology ; Chemistry, Multidisciplinary
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收录类别sci
资助项目LMB
WOS记录号WOS:000265475200011
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文献类型期刊论文
条目标识符http://ir.scsio.ac.cn/handle/344004/5124
专题中科院海洋生物资源可持续利用重点实验室
通讯作者haoxj@mail.kib.ac.cn
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Yang, XW,He, HP,Du, ZZ,et al. Tarennanosides A-H, Eight New Lignan Glucosides from Tarenna attenuata and Their Protective Effect on H2O2-Induced Impairment in PC12 Cells[J]. CHEMISTRY & BIODIVERSITY,2009,6(4):540-550.
APA Yang, XW.,He, HP.,Du, ZZ.,Liu, HY.,Di, YT.,...&haoxj@mail.kib.ac.cn.(2009).Tarennanosides A-H, Eight New Lignan Glucosides from Tarenna attenuata and Their Protective Effect on H2O2-Induced Impairment in PC12 Cells.CHEMISTRY & BIODIVERSITY,6(4),540-550.
MLA Yang, XW,et al."Tarennanosides A-H, Eight New Lignan Glucosides from Tarenna attenuata and Their Protective Effect on H2O2-Induced Impairment in PC12 Cells".CHEMISTRY & BIODIVERSITY 6.4(2009):540-550.
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