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学科主题: Biochemistry & Molecular Biology; Chemistry, Multidisciplinary
题名: Tarennanosides A-H, Eight New Lignan Glucosides from Tarenna attenuata and Their Protective Effect on H2O2-Induced Impairment in PC12 Cells
作者: Yang, XW ; He, HP ; Du, ZZ ; Liu, HY ; Di, YT ; Ma, YL ; Wang, F ; Lin, H ; Zuo, YQ ; Li, L ; Hao, XJ
通讯作者: haoxj@mail.kib.ac.cn
刊名: CHEMISTRY & BIODIVERSITY
发表日期: 2009
卷: 6, 期:4, 页:540-550
收录类别: sci
部门归属: [Yang, Xian-Wen; He, Hong-Ping; Du, Zhi-Zhi; Liu, Hai-Yang; Di, Ying-Tong; Hao, Xiao-Jiang] Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources W China, Kunming 650204, Peoples R China; [Yang, Xian-Wen] Chinese Acad Sci, S China Sea Inst Oceanol, Key Lab Marine Bioresources Sustainable Utilizat, Guangzhou 510301, Guangdong, Peoples R China; [Ma, Yan-Lin; Wang, Fang; Lin, Hua; Zuo, Yi-Qing; Li, Ling] Kunming Med Coll, Yunnan Pharmacol Labs Nat Prod, Kunming 650031, Peoples R China
项目归属: LMB
摘要: Eight new lignan glucosides, tarennanosides A-H (1-8, resp.), were isolated from the whole plant of Tarenna attenuata, together with three known compounds, fernandoside, (-)-lyoniresinol, and (-)isolariciresinol. The planar structures of new compounds were elucidated mainly by analysis of physical and spectroscopic data, and the absolute configurations were determined by acid hydrolysis as well as CD spectroscopy. Compounds I and 2 exhibited potent antioxidant activities against H2O2-induced impairment in PC12 cells. Preliminary mechanism study by the 1,1-diphenyl-2-picrylhydrazyl (DPPH) method showed that these two compounds could act as radical scavengers.
原文出处: 查看原文
WOS记录号: WOS:000265475200011
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内容类型: 期刊论文
URI标识: http://ir.scsio.ac.cn/handle/344004/5124
Appears in Collections:中科院海洋生物资源可持续利用重点实验室_期刊论文

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Yang, XW; He, HP; Du, ZZ; Liu, HY; Di, YT; Ma, YL; Wang, F; Lin, H; Zuo, YQ; Li, L; Hao, XJ.Tarennanosides A-H, Eight New Lignan Glucosides from Tarenna attenuata and Their Protective Effect on H2O2-Induced Impairment in PC12 Cells,CHEMISTRY & BIODIVERSITY,2009,6(4):540-550
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