Antifeedant and antifouling briaranes from the South China Sea gorgonian Junceella juncea
Qi, SH; Zhang, S; Qian, PY; Xu, HH; shuhuaqi2001@yahoo.com
2009
发表期刊CHEMISTRY OF NATURAL COMPOUNDS
ISSN0009-3130
卷号45期号:1页码:49-54
摘要A new briarane diterpene, juncin ZII (1), along with three known briaranes (2-4), was isolated from the EtOH/CH2Cl2 extracts of the South China Sea gorgonian Junceella juncea. The structure of 1 was established by extensive spectroscopic analysis, including 1D and 2D NMR data. For compounds 1-4 and eight other briaranes (5-12) isolated from J. juncea previously, the antifeedant activity against second-instar larvae of Spodoptera litura and cytotoxicity against S. litura cells were investigated, and it was observed that they all exhibit medium antifeedant activity. Compounds 1, 8, 9, and 12 also showed potent antifouling activity against the larval settlement of barnacle Balanus amphitrite at nontoxic concentrations with EC50 values of 0.004, 0.005, 2.82, and 0.447 mu g/mL, respectively, while all compounds did not show obvious cytotoxicity against tumor cell lines K562, A549, Hela, and Hep-2. Their structure-activity relationship was discussed.
部门归属[Qi, S. H.; Zhang, S.] Chinese Acad Sci, S China Sea Inst Oceanol, Guangdong Key Lab Marine Mat Med, Guangzhou 510301, Guangdong, Peoples R China; [Qian, P. Y.] Hong Kong Univ Sci & Technol, Dept Biol, CML, Kln, Hong Kong, Peoples R China; [Xu, H. H.] S China Agr Univ, Coll Resources & Environm, Guangzhou 510642, Guangdong, Peoples R China
关键词Junceella Juncea Briaranes Antifeedant Cytotoxicity Antifouling Structure-activity Relationship
学科领域Chemistry, Organic
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收录类别sci
资助项目LMB
WOS记录号WOS:000265037900012
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被引频次:20[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.scsio.ac.cn/handle/344004/5128
专题中科院海洋生物资源可持续利用重点实验室
通讯作者shuhuaqi2001@yahoo.com
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Qi, SH,Zhang, S,Qian, PY,et al. Antifeedant and antifouling briaranes from the South China Sea gorgonian Junceella juncea[J]. CHEMISTRY OF NATURAL COMPOUNDS,2009,45(1):49-54.
APA Qi, SH,Zhang, S,Qian, PY,Xu, HH,&shuhuaqi2001@yahoo.com.(2009).Antifeedant and antifouling briaranes from the South China Sea gorgonian Junceella juncea.CHEMISTRY OF NATURAL COMPOUNDS,45(1),49-54.
MLA Qi, SH,et al."Antifeedant and antifouling briaranes from the South China Sea gorgonian Junceella juncea".CHEMISTRY OF NATURAL COMPOUNDS 45.1(2009):49-54.
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