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学科主题: Chemistry, Organic
题名: Antifeedant and antifouling briaranes from the South China Sea gorgonian Junceella juncea
作者: Qi, SH ; Zhang, S ; Qian, PY ; Xu, HH
通讯作者: shuhuaqi2001@yahoo.com
关键词: Junceella juncea ; briaranes ; antifeedant ; cytotoxicity ; antifouling ; structure-activity relationship
刊名: CHEMISTRY OF NATURAL COMPOUNDS
发表日期: 2009
卷: 45, 期:1, 页:49-54
收录类别: sci
部门归属: [Qi, S. H.; Zhang, S.] Chinese Acad Sci, S China Sea Inst Oceanol, Guangdong Key Lab Marine Mat Med, Guangzhou 510301, Guangdong, Peoples R China; [Qian, P. Y.] Hong Kong Univ Sci & Technol, Dept Biol, CML, Kln, Hong Kong, Peoples R China; [Xu, H. H.] S China Agr Univ, Coll Resources & Environm, Guangzhou 510642, Guangdong, Peoples R China
项目归属: LMB
摘要: A new briarane diterpene, juncin ZII (1), along with three known briaranes (2-4), was isolated from the EtOH/CH2Cl2 extracts of the South China Sea gorgonian Junceella juncea. The structure of 1 was established by extensive spectroscopic analysis, including 1D and 2D NMR data. For compounds 1-4 and eight other briaranes (5-12) isolated from J. juncea previously, the antifeedant activity against second-instar larvae of Spodoptera litura and cytotoxicity against S. litura cells were investigated, and it was observed that they all exhibit medium antifeedant activity. Compounds 1, 8, 9, and 12 also showed potent antifouling activity against the larval settlement of barnacle Balanus amphitrite at nontoxic concentrations with EC50 values of 0.004, 0.005, 2.82, and 0.447 mu g/mL, respectively, while all compounds did not show obvious cytotoxicity against tumor cell lines K562, A549, Hela, and Hep-2. Their structure-activity relationship was discussed.
原文出处: 查看原文
WOS记录号: WOS:000265037900012
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内容类型: 期刊论文
URI标识: http://ir.scsio.ac.cn/handle/344004/5128
Appears in Collections:中科院海洋生物资源可持续利用重点实验室_期刊论文

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Recommended Citation:
Qi, SH; Zhang, S; Qian, PY; Xu, HH.Antifeedant and antifouling briaranes from the South China Sea gorgonian Junceella juncea,CHEMISTRY OF NATURAL COMPOUNDS,2009,45(1):49-54
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文件名: Antifeedant and antifouling briaranes from the South China Sea gorgonian Junceella juncea .pdf
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