SCSIO OpenIR  > 广东省海洋药物重点实验室
A new lignan from the Jian-er syrup and its content determination by RP-HPLC
Yang, MH; Wu, J; Xu, XD; Jin, Y; Guo, Y; Chen, JM; yangmeihua15@hotmail.com
2006
发表期刊JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS
ISSN0731-7085
卷号41期号:2页码:662-666
摘要The Jian-er syrup is a commonly used traditional Chinese medicinal preparation refined from two herbs, Metaplexis japonica (Thunb.) Makino and Justicia procumbens L. A new lignan, named 6'-hydroxy-Justicidin B, was isolated from the ethyl acetate extract of the Jian-er syrup and its structure was established on the basis of spectral analysis. The content of 6'-hydroxy-Justicidin B in the Jian-er syrup was determined by RP-HPLC for the first time. Chromatographic separation was achieved on an Agilent Zorbax SB-C-18 column (150 mm x 4.6 mm i.d., 5 mu m) at 25 degrees C and the mobile phase was a mixture of acetonitrile and water (31:69 v/v) detected at 256 nm at a flow rate of 1.0 ml/min. This method was validated in terms of selectivity, linearity, precision, accuracy, limit of detection, limit of quantitation and solution stability. It can be used to control the quality of this preparation effectively. (c) 2005 Elsevier B.V. All rights reserved.
部门归属Chinese Acad Med Sci, Inst Med Plant Dev, Beijing 100094, Peoples R China; Peking Union Med Coll, Beijing 100094, Peoples R China; Chinese Acad Sci, S China Sea Inst Oceanol, Guangdong Key Lab Marine Mat Med, Guangzhou 510301, Peoples R China
关键词Lignan 6 '-hydroxy-justicidin b Structural Elucidation Content Determination High Performance Liquid Chromatography The Jian-er Syrup
学科领域Chemistry, Analytical ; Pharmacology & Pharmacy
URL查看原文
收录类别sci
资助项目广东省海洋药物重点实验室
WOS记录号WOS:000237705700049
引用统计
被引频次:14[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.scsio.ac.cn/handle/344004/5200
专题广东省海洋药物重点实验室
通讯作者yangmeihua15@hotmail.com
推荐引用方式
GB/T 7714
Yang, MH,Wu, J,Xu, XD,et al. A new lignan from the Jian-er syrup and its content determination by RP-HPLC[J]. JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS,2006,41(2):662-666.
APA Yang, MH.,Wu, J.,Xu, XD.,Jin, Y.,Guo, Y.,...&yangmeihua15@hotmail.com.(2006).A new lignan from the Jian-er syrup and its content determination by RP-HPLC.JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS,41(2),662-666.
MLA Yang, MH,et al."A new lignan from the Jian-er syrup and its content determination by RP-HPLC".JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS 41.2(2006):662-666.
条目包含的文件
文件名称/大小 文献类型 版本类型 开放类型 使用许可
A new lignan from th(137KB) 开放获取--请求全文
个性服务
推荐该条目
保存到收藏夹
查看访问统计
导出为Endnote文件
相关权益政策
暂无数据
收藏/分享
所有评论 (0)
暂无评论
 

除非特别说明,本系统中所有内容都受版权保护,并保留所有权利。