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Furostanol saponins with inhibitory action against COX-2 production from Tupistra chinensis rhizomes
Zou, K; Wang, JZ; Wu, J; Zhou, Y; Liu, C; Dan, FJ; Zhang, YX; Yang, J; kzou@ctgu.edu.cn
2007
发表期刊CHINESE CHEMICAL LETTERS
ISSN1001-8417
卷号18期号:10页码:1239-1242
摘要Two furostanol saponins were obtained from the n-butanol fraction of methanol extract from Tupistra chinensis rhizomes, a folk medicine of Shennongjia Forest District of Hubei Province. Their structures were determinedas (25S)-26-O-(beta-D-glucopyranosyl)-furost-1 beta, 3 beta, 22 alpha, 26-tetrol-3-O-beta-D-glucopyranosyl-(1 -> 4)-beta-D-glucopyranosyl-(l -> 2)-beta-D-glucopyranoside (1) and (25R)26-O-(beta-D-glucopyranosyl)-furost-1 beta, 3 beta 22a, 26-tetrol 3-O-beta-D-glucopyranosyl-(l -> 4)-beta-D-glucopyranosyl-(l -> 2)-beta-D-glucopyranoside (2), on basis of chemical and spectroscopic evidences. 1 and 2 displayed marked inhibitory action towards COX-2 production in macrophages of the rat abdomen induced by LPS at 20 mu g/mL. (c) 2007 Kun Zou. Published by Elsevier B.V. on behalf of Chinese Chemical Society. All rights reserved.
部门归属China Three Gorges Univ, Coll Chem & Life Sci, Hubei Prov Key Lab Nat Prod Res & Dev, Yichang 443002, Peoples R China; Chinese Acad Sci, S China Sea Inst Oceanol, Guangdong Key Lab Marine Mat Med, Guangzhou 510301, Peoples R China
关键词Tupistra Chinensis Bak. Furostanol Saponin Cox-2 Folk Medicines
学科领域Chemistry, Multidisciplinary
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收录类别sci
资助项目广东省海洋药物重点实验室
WOS记录号WOS:000250494100022
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被引频次:12[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.scsio.ac.cn/handle/344004/5214
专题广东省海洋药物重点实验室
通讯作者kzou@ctgu.edu.cn
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GB/T 7714
Zou, K,Wang, JZ,Wu, J,et al. Furostanol saponins with inhibitory action against COX-2 production from Tupistra chinensis rhizomes[J]. CHINESE CHEMICAL LETTERS,2007,18(10):1239-1242.
APA Zou, K.,Wang, JZ.,Wu, J.,Zhou, Y.,Liu, C.,...&kzou@ctgu.edu.cn.(2007).Furostanol saponins with inhibitory action against COX-2 production from Tupistra chinensis rhizomes.CHINESE CHEMICAL LETTERS,18(10),1239-1242.
MLA Zou, K,et al."Furostanol saponins with inhibitory action against COX-2 production from Tupistra chinensis rhizomes".CHINESE CHEMICAL LETTERS 18.10(2007):1239-1242.
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