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学科主题: Chemistry, Multidisciplinary
题名: Furostanol saponins with inhibitory action against COX-2 production from Tupistra chinensis rhizomes
作者: Zou, K ; Wang, JZ ; Wu, J ; Zhou, Y ; Liu, C ; Dan, FJ ; Zhang, YX ; Yang, J
通讯作者: kzou@ctgu.edu.cn
关键词: Tupistra chinensis bak. ; furostanol saponin ; COX-2 ; folk medicines
刊名: CHINESE CHEMICAL LETTERS
发表日期: 2007
卷: 18, 期:10, 页:1239-1242
收录类别: sci
部门归属: China Three Gorges Univ, Coll Chem & Life Sci, Hubei Prov Key Lab Nat Prod Res & Dev, Yichang 443002, Peoples R China; Chinese Acad Sci, S China Sea Inst Oceanol, Guangdong Key Lab Marine Mat Med, Guangzhou 510301, Peoples R China
项目归属: 广东省海洋药物重点实验室
摘要: Two furostanol saponins were obtained from the n-butanol fraction of methanol extract from Tupistra chinensis rhizomes, a folk medicine of Shennongjia Forest District of Hubei Province. Their structures were determinedas (25S)-26-O-(beta-D-glucopyranosyl)-furost-1 beta, 3 beta, 22 alpha, 26-tetrol-3-O-beta-D-glucopyranosyl-(1 -> 4)-beta-D-glucopyranosyl-(l -> 2)-beta-D-glucopyranoside (1) and (25R)26-O-(beta-D-glucopyranosyl)-furost-1 beta, 3 beta 22a, 26-tetrol 3-O-beta-D-glucopyranosyl-(l -> 4)-beta-D-glucopyranosyl-(l -> 2)-beta-D-glucopyranoside (2), on basis of chemical and spectroscopic evidences. 1 and 2 displayed marked inhibitory action towards COX-2 production in macrophages of the rat abdomen induced by LPS at 20 mu g/mL. (c) 2007 Kun Zou. Published by Elsevier B.V. on behalf of Chinese Chemical Society. All rights reserved.
原文出处: 查看原文
WOS记录号: WOS:000250494100022
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内容类型: 期刊论文
URI标识: http://ir.scsio.ac.cn/handle/344004/5214
Appears in Collections:广东省海洋药物重点实验室_期刊论文

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Recommended Citation:
Zou, K; Wang, JZ; Wu, J; Zhou, Y; Liu, C; Dan, FJ; Zhang, YX; Yang, J.Furostanol saponins with inhibitory action against COX-2 production from Tupistra chinensis rhizomes,CHINESE CHEMICAL LETTERS,2007,18(10):1239-1242
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