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An 18-norspirostanol saponin with inhibitory action against COX-2 production from the underground part of Trillium tschonoskii
Wang, JZ; Zou, K; Zhang, YM; Liu, C; Wu, J; Zhou, Y; Dan, FJ; Zhang, YX; kzou@ctgu.edu.cn
2007
发表期刊CHEMICAL & PHARMACEUTICAL BULLETIN
ISSN0009-2363
卷号55期号:4页码:679-681
摘要A novel 18-norspirostanol saponin (1), along with Trillenoside A (2), was obtained from the underground parts of Trillium tschonoskii MAXIM., collected in Shennongjia Forest District, China. Based on the chemical and spectroscopic evidences, their structures were determined as shown in Fig. 1. 1 and 2 displayed marked inhibitory action towards COX-2 production in macrophagocytes of the mouse abdominal cavity stimulated by LPS at 10 mu g/ml.
部门归属China Three Gorges Univ, Coll Chem & Life Sci, Hubei Key Lab Nat Prod Res & Dev, Yichang 443002, Peoples R China; Chinese Acad Sci, S China Sea Isnt Oceanol, Guangdong Key Lab Marine Mat Med, Guangzhou 510301, Peoples R China
关键词Trillium Tschonoskii 18-norspirostanol Saponin Cox-2 Folk Medicine Trillenoside a
学科领域Chemistry, Medicinal ; Chemistry, Multidisciplinary ; Pharmacology & Pharmacy
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收录类别sci
资助项目广东省海洋药物重点实验室
WOS记录号WOS:000246377800036
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文献类型期刊论文
条目标识符http://ir.scsio.ac.cn/handle/344004/5236
专题广东省海洋药物重点实验室
通讯作者kzou@ctgu.edu.cn
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GB/T 7714
Wang, JZ,Zou, K,Zhang, YM,et al. An 18-norspirostanol saponin with inhibitory action against COX-2 production from the underground part of Trillium tschonoskii[J]. CHEMICAL & PHARMACEUTICAL BULLETIN,2007,55(4):679-681.
APA Wang, JZ.,Zou, K.,Zhang, YM.,Liu, C.,Wu, J.,...&kzou@ctgu.edu.cn.(2007).An 18-norspirostanol saponin with inhibitory action against COX-2 production from the underground part of Trillium tschonoskii.CHEMICAL & PHARMACEUTICAL BULLETIN,55(4),679-681.
MLA Wang, JZ,et al."An 18-norspirostanol saponin with inhibitory action against COX-2 production from the underground part of Trillium tschonoskii".CHEMICAL & PHARMACEUTICAL BULLETIN 55.4(2007):679-681.
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