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学科主题: Pediatrics
题名: Retrospective analysis of Mycoplasma pneumoniae in pediatric fatal infection pneumonia in Guangzhou, South China
作者: Ou, ZY ; Zhou, R ; Wang, FH ; Lu, JP ; Xia, JQ ; Xia, HM ; Zhang, JT ; Gong, ST ; Deng, L ; Wu, ZH ; Zeng, QY
通讯作者: gzcentralab@yahoo.com.cn
关键词: mycoplasma pneumoniae ; fatal pneumonia ; pulmonary tissue ; nested PCR ; immunohistochemistry
刊名: CLINICAL PEDIATRICS
发表日期: 2008
卷: 47, 期:8, 页:791-796
收录类别: sci
部门归属: [Ou, Zhi-Ying; Zhou, Rong; Wang, Feng-Hua; Xia, Jian-Qing; Xia, Hui-Min; Zhang, Jian-Tao; Gong, Si-Tang; Deng, Li; Zeng, Qi-Yi] Guangzhou Childrens Hosp, Guangzhou 510120, Peoples R China; [Zhou, Rong; Wu, Zao-He] Chinese Acad Sci, LED, S China Sea Inst Oceanol, Beijing 100864, Peoples R China; [Lu, Jun-Peng] S China Agr Univ, Coll Vet Med, Guangzhou, Peoples R China; [Zhou, Rong; Wu, Zao-He] Chinese Acad Sci, Grad Sch, Beijing, Peoples R China
项目归属: 广东省海洋药物重点实验室
摘要: The objective of this study is to investigate the infection and distribution of Mycoplasma pneumoniae in autopsied pulmonary tissue of pediatric severe pneumonia. Mycoplasma pneumoniae nested polymerase chain reaction and immunohistochemistry were done Oil autopsy pulmonary tissue from 173 patients who died of severe pneumonia. Mycoplasma pneumoniae was identified in 135/173 (78.03%) and 114/173 (65.89%) samples of autopsied pulmonary tissue of lethal severe pneumonia via nested polymerase chain reaction and immunohistochemistry, respectively The coincidence of both assays was 92.4%. Mycoplasma pneumoniae associated Fatal pneumonia has showed all increasing trend from 1988 to 2005 in South China, and the fatality rate of Mycoplasma pneumoniae associated fatal pneumonia in infants, I to 12 months, has risen to 66.9% (97/145). Mycoplasma pneumoniae is a significant cause of severe pneumonia, it is a universal event in infants, and children have died OF Severe pneumonia ill South China. Mycoplasma pneumoniae might be an important pathogen responsible For fatal pneumonia in Guangzhou area, South China.
原文出处: 查看原文
WOS记录号: WOS:000259165500009
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内容类型: 期刊论文
URI标识: http://ir.scsio.ac.cn/handle/344004/5264
Appears in Collections:广东省海洋药物重点实验室_期刊论文

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Recommended Citation:
Ou, ZY; Zhou, R; Wang, FH; Lu, JP; Xia, JQ; Xia, HM; Zhang, JT; Gong, ST; Deng, L; Wu, ZH; Zeng, QY.Retrospective analysis of Mycoplasma pneumoniae in pediatric fatal infection pneumonia in Guangzhou, South China,CLINICAL PEDIATRICS,2008,47(8):791-796
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