SCSIO OpenIR  > 海洋生物
Growth-associated biosynthesis of astaxanthin in heterotrophic Chlorella zofingiensis (Chlorophyta)
Wang, Y; Peng, J; ywang@yic.ac.cn
2008
发表期刊WORLD JOURNAL OF MICROBIOLOGY & BIOTECHNOLOGY
ISSN0959-3993
卷号24期号:9页码:1915-1922
摘要The green microalga Chlorella zofingiensis can produce the ketocarotenoid astaxanthin under heterotrophic culture conditions. Here we report the growth-associated biosynthesis of astaxanthin in this biotechnologically important alga. With glucose as sole carbon and energy source, C. zofinginesis grew fast in the dark with rapid exhaustion of nitrogen and carbon sources from media, leading to a high specific growth rate (0.034 h(-1)). Cultures started at a cell concentration of about 3.4 x 10(9) cells l(-1) reached, after 6 days, standing biomass values of 1.6 x 10(11) cells or 8.5 g dry weight l(-1). Surprisingly, the biosynthesis of astaxanthin was found to start at early exponential phase, independent of cessation of cell division. A general trend was observed that the culture conditions benefiting cell growth also benefited astaxanthin accumulation, indicating that astaxanthin was a growth-associated product in this alga. The maximum cell dry biomass and astaxanthin yield were 11.75 g l(-1) and 11.14 mg l(-1) (about 1 mg g(-1)), simultaneously obtained in the fed-batch culture with a combined glucose-nitrate mixture addition, which were the highest ever reported in dark-heterotrophic algal cultures. The possible reasons why dark-heterotrophic C. zofingiensis could produce astaxanthin during the course of cell growth were discussed.
部门归属[Wang, Y.] Chinese Acad Sci, Yantai Inst Coastal Zone Res Sustainable Dev, Yantai 264003, Shandong, Peoples R China; [Wang, Y.; Peng, J.] Chinese Acad Sci, S China Sea Inst Oceanol, Guangzhou, Guangdong, Peoples R China
关键词Astaxanthin Chlorella Zofingiensis Glucose Heterotrophic Culture
学科领域Biotechnology & Applied Microbiology
URL查看原文
收录类别sci
WOS记录号WOS:000257961500036
引用统计
文献类型期刊论文
条目标识符http://ir.scsio.ac.cn/handle/344004/5364
专题海洋生物
通讯作者ywang@yic.ac.cn
推荐引用方式
GB/T 7714
Wang, Y,Peng, J,ywang@yic.ac.cn. Growth-associated biosynthesis of astaxanthin in heterotrophic Chlorella zofingiensis (Chlorophyta)[J]. WORLD JOURNAL OF MICROBIOLOGY & BIOTECHNOLOGY,2008,24(9):1915-1922.
APA Wang, Y,Peng, J,&ywang@yic.ac.cn.(2008).Growth-associated biosynthesis of astaxanthin in heterotrophic Chlorella zofingiensis (Chlorophyta).WORLD JOURNAL OF MICROBIOLOGY & BIOTECHNOLOGY,24(9),1915-1922.
MLA Wang, Y,et al."Growth-associated biosynthesis of astaxanthin in heterotrophic Chlorella zofingiensis (Chlorophyta)".WORLD JOURNAL OF MICROBIOLOGY & BIOTECHNOLOGY 24.9(2008):1915-1922.
条目包含的文件
文件名称/大小 文献类型 版本类型 开放类型 使用许可
Growth-associated bi(261KB) 开放获取--请求全文
个性服务
推荐该条目
保存到收藏夹
查看访问统计
导出为Endnote文件
相关权益政策
暂无数据
收藏/分享
所有评论 (0)
暂无评论
 

除非特别说明,本系统中所有内容都受版权保护,并保留所有权利。