Identification and mapping of disease-resistance QTLs in the eastern oyster, Crassostrea virginica Gmelin
Yu, ZN; Guo, XM; xguo@hsrl.rutgers.edu
2006
发表期刊AQUACULTURE
ISSN0044-8486
卷号254期号:40547页码:160-170
摘要Identification and mapping of disease-resistance QTLs (quantitative trait loci) is important for our understanding of genetic mechanisms of disease-resistance and for our ability to genetically improve cultured stocks. Disease-resistance is the most important trait for farmers of the eastern oyster (Crassostrea virginica Gmelin), which is affected by two major diseases: MSX and Dermo. In this study, the genome of the eastern oyster was scanned with a large number of amplified fragment length polymorphism (AFLP) markers before and after Dermo-inflicted mortalities (53% and 67%) in two reference families. Significant post-mortality shifts in genotype frequency were detected at a large number of loci. Linkage analysis revealed that most markers showing frequency shifts are closely linked to each other on the genetic map, and all markers within a cluster had frequency shifts in the same direction according to their linkage phase. This finding suggests that post-mortality shifts in genotype frequency were not random, but linked to Dermo/summer mortality-resistance QTLs. Twelve putative Dermo/summer mortality-resistance QTLs were identified on female and male maps from two families, providing candidate genome regions for further analysis. (c) 2005 Elsevier B.V All rights reserved.
部门归属Rutgers State Univ, Inst Marine & Coastal Sci, Haskin Shellfish Res Lab, Port Norris, NJ 08349 USA; Chinese Acad Sci, S China Sea Inst Oceanol, Appl Marine Biol Lab, Guangzhou 510301, Guangdong, Peoples R China
关键词Disease-resistance Linkage Mapping Aflp Markers Qtls Dermo Summer Mortality Oyster Crassostrea Virginica
学科领域Fisheries ; Marine & Freshwater Biology
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收录类别sci
资助项目广东省应用海洋生物学重点实验室
WOS记录号WOS:000237838800019
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被引频次:61[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.scsio.ac.cn/handle/344004/5460
专题广东省应用海洋生物学重点实验室
通讯作者xguo@hsrl.rutgers.edu
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Yu, ZN,Guo, XM,xguo@hsrl.rutgers.edu. Identification and mapping of disease-resistance QTLs in the eastern oyster, Crassostrea virginica Gmelin[J]. AQUACULTURE,2006,254(40547):160-170.
APA Yu, ZN,Guo, XM,&xguo@hsrl.rutgers.edu.(2006).Identification and mapping of disease-resistance QTLs in the eastern oyster, Crassostrea virginica Gmelin.AQUACULTURE,254(40547),160-170.
MLA Yu, ZN,et al."Identification and mapping of disease-resistance QTLs in the eastern oyster, Crassostrea virginica Gmelin".AQUACULTURE 254.40547(2006):160-170.
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