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学科主题: Fisheries; Marine & Freshwater Biology
题名: Identification and mapping of disease-resistance QTLs in the eastern oyster, Crassostrea virginica Gmelin
作者: Yu, ZN ; Guo, XM
通讯作者: xguo@hsrl.rutgers.edu
关键词: disease-resistance ; linkage mapping ; AFLP markers ; QTLs ; Dermo ; summer mortality ; oyster ; Crassostrea virginica
刊名: AQUACULTURE
发表日期: 2006
卷: 254, 期:40547, 页:160-170
收录类别: sci
部门归属: Rutgers State Univ, Inst Marine & Coastal Sci, Haskin Shellfish Res Lab, Port Norris, NJ 08349 USA; Chinese Acad Sci, S China Sea Inst Oceanol, Appl Marine Biol Lab, Guangzhou 510301, Guangdong, Peoples R China
项目归属: 广东省应用海洋生物学重点实验室
摘要: Identification and mapping of disease-resistance QTLs (quantitative trait loci) is important for our understanding of genetic mechanisms of disease-resistance and for our ability to genetically improve cultured stocks. Disease-resistance is the most important trait for farmers of the eastern oyster (Crassostrea virginica Gmelin), which is affected by two major diseases: MSX and Dermo. In this study, the genome of the eastern oyster was scanned with a large number of amplified fragment length polymorphism (AFLP) markers before and after Dermo-inflicted mortalities (53% and 67%) in two reference families. Significant post-mortality shifts in genotype frequency were detected at a large number of loci. Linkage analysis revealed that most markers showing frequency shifts are closely linked to each other on the genetic map, and all markers within a cluster had frequency shifts in the same direction according to their linkage phase. This finding suggests that post-mortality shifts in genotype frequency were not random, but linked to Dermo/summer mortality-resistance QTLs. Twelve putative Dermo/summer mortality-resistance QTLs were identified on female and male maps from two families, providing candidate genome regions for further analysis. (c) 2005 Elsevier B.V All rights reserved.
原文出处: 查看原文
WOS记录号: WOS:000237838800019
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内容类型: 期刊论文
URI标识: http://ir.scsio.ac.cn/handle/344004/5460
Appears in Collections:广东省应用海洋生物学重点实验室_期刊论文

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Recommended Citation:
Yu, ZN; Guo, XM.Identification and mapping of disease-resistance QTLs in the eastern oyster, Crassostrea virginica Gmelin,AQUACULTURE,2006,254(40547):160-170
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文件名: Identification and mapping of disease-resistance QTLs in the eastern oyster, Crassostrea virginica Gmelin .pdf
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