中国科学院南海海洋研究所机构知识库
Advanced  
SCSIO OpenIR  > 热带海洋环境国家重点实验室(LTO)  > 期刊论文
学科主题: Environmental Sciences; Toxicology
题名: The ratios of individual chemicals in a mixture determine the degree of joint effect: The climax hypothesis
作者: Lin, Z ; Ping, Z ; Kong, D ; Yin, K ; Cai, Z
通讯作者: lzhifen@yahoo.com
刊名: ARCHIVES OF ENVIRONMENTAL CONTAMINATION AND TOXICOLOGY
发表日期: 2005
卷: 49, 期:1, 页:40551
收录类别: sci
部门归属: Chinese Acad Sci, S China Sea Inst Oceanol, Key Lab Trop Marine Environm Dynam, Guangzhou 510301, Peoples R China; Chinese Acad Fishery Sci, E China Sea Fisheries Res Inst, Minist Agr, Key Lab Marine & Estuarine Fisheries, Shanghai 200090, Peoples R China; Jinan Univ, Inst Hydrobiol, Guangzhou 510632, Peoples R China; Natl Environm Protect Agcy, Nanjing Inst Environm Sci, Nanjing 210042, Peoples R China; Chinese Acad Sci, S China Sea Inst Oceanol, Dept Appl Marine Biol, Guangzhou 510301, Peoples R China
项目归属: LED
摘要: A new hypothesis, the Climax Hypothesis, is proposed to describe how the ratios of individual chemicals influence the joint effects of chemical mixtures. This hypothesis is derived from a generalized approach using "isobolograms." With this hypothesis, one can predict that for a given mixture, a curvilinear correlation exists between the joint effects and the ratios of individual chemicals and that this curve has a climax at the equitoxic ratio. This prediction is supported by the observed toxicity to Vibrio fischeri of 18 mixtures (12 binary mixtures, 4 ternary mixtures, and 2 quaternary mixtures). With this prediction, the Climax Hypothesis has some promising applications such as controlling the discharge of effluents in environmental science, maximizing detoxifying effects in medicine, and optimizing combined pesticides in agriculture.
WOS记录号: WOS:000230565000001
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.scsio.ac.cn/handle/344004/5709
Appears in Collections:热带海洋环境动力实验室(LTO)_期刊论文

Files in This Item: Download All
File Name/ File Size Content Type Version Access License
The Ratios of Individual Chemicals in a Mixture Determine the Degree of Joint Effect The Climax Hypothesis .pdf(320KB)----开放获取--View Download

Recommended Citation:
Lin, Z; Ping, Z; Kong, D; Yin, K; Cai, Z.The ratios of individual chemicals in a mixture determine the degree of joint effect: The climax hypothesis,ARCHIVES OF ENVIRONMENTAL CONTAMINATION AND TOXICOLOGY,2005,49(1):40551
Service
Recommend this item
Sava as my favorate item
Show this item's statistics
Export Endnote File
Google Scholar
Similar articles in Google Scholar
[Lin, Z]'s Articles
[Ping, Z]'s Articles
[Kong, D]'s Articles
CSDL cross search
Similar articles in CSDL Cross Search
[Lin, Z]‘s Articles
[Ping, Z]‘s Articles
[Kong, D]‘s Articles
Related Copyright Policies
Null
Social Bookmarking
Add to CiteULike Add to Connotea Add to Del.icio.us Add to Digg Add to Reddit
文件名: The Ratios of Individual Chemicals in a Mixture Determine the Degree of Joint Effect The Climax Hypothesis .pdf
格式: Adobe PDF
所有评论 (0)
暂无评论
 
评注功能仅针对注册用户开放,请您登录
您对该条目有什么异议,请填写以下表单,管理员会尽快联系您。
内 容:
Email:  *
单位:
验证码:   刷新
您在IR的使用过程中有什么好的想法或者建议可以反馈给我们。
标 题:
 *
内 容:
Email:  *
验证码:   刷新

Items in IR are protected by copyright, with all rights reserved, unless otherwise indicated.

 

 

Valid XHTML 1.0!
Copyright © 2007-2017  中国科学院南海海洋研究所 - Feedback
Powered by CSpace