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Influence of hydroxypropylcyclodextrins on the toxicity of mixtures
Lin, ZF; Kong, DY; Zhong, P; Yin, KD; Dong, LH;
Source PublicationCHEMOSPHERE
AbstractWe studied the influence of hydroxypropylcyclodextrins (HPCDs) on the toxicity of some mixtures. Using the Photobacterium phosphoreum toxicity test, the joint toxicological effect for Mixture I (containing p-nitrobenzaldehyde and 1-nitronaphthalene) and Mixture 11 (containing p-nitrobenzaldehyde and malononitrile) were determined in water and in aqueous solutions of HPCDs. The results indicate that, although the toxicological joint effect for Mixture I (simple addition) differs from that of Mixture 11 (synergism), alpha- and beta-HPCD can significantly reduce the toxicity of the test compounds, whereas gamma-HPCD has only a slight effect. Explanations for these observations are given that invoke the molecular structure of the individual chemicals as well as the structures of HPCDs. This provides information to assist the application of HPCDs in remediation of environmental pollution. (C) 2004 Elsevier Ltd. All rights reserved.
DepartmentChinese Acad Sci, S China Sea Inst Oceanol, Key Lab Trop Marine Environm Dynam, Guangzhou 510301, Peoples R China; Chinese Acad Fishery Sci, E China Sea Fisheries Res Inst, Minist Agr, Key Lab Marine & Esturaine Fisheries, Shanghai 200090, Peoples R China; Natl Environm Protect Agcy, Nanjing Inst Environm Sci, Nanjing 210042, Peoples R China; Jinan Univ, Inst Hydrobiol, Guangzhou 510632, Peoples R China
KeywordHydroxypropylcyclodextrins (Hpcds) Toxicity Of Mixtures Molecular Structure Photobacterium Phosphoreum
Subject AreaEnvironmental Sciences
Indexed Bysci
Funding ProjectLED
WOS IDWOS:000227375500016
Citation statistics
Cited Times:8[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Recommended Citation
GB/T 7714
Lin, ZF,Kong, DY,Zhong, P,et al. Influence of hydroxypropylcyclodextrins on the toxicity of mixtures[J]. CHEMOSPHERE,2005,58(9):1301-1306.
APA Lin, ZF,Kong, DY,Zhong, P,Yin, KD,Dong, LH,& of hydroxypropylcyclodextrins on the toxicity of mixtures.CHEMOSPHERE,58(9),1301-1306.
MLA Lin, ZF,et al."Influence of hydroxypropylcyclodextrins on the toxicity of mixtures".CHEMOSPHERE 58.9(2005):1301-1306.
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