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学科主题: Chemistry, Organic
题名: Abiestetranes A and B, two unique tetraterpenes from Abies fabri
作者: Li, YL ; Zhang, SD ; Jin, HZ ; Tian, JM ; Shen, YH ; Yang, XW ; Li, HL ; Zhang, WD
通讯作者: xwyang@scsio.ac.cn ; wdzhangy@hotmail.com
关键词: Abies fabri ; Pinaceae ; Diels-Alder cycloaddition ; Tetraterpenes ; Abiestetranes A and B ; Cytotoxicity
刊名: TETRAHEDRON
发表日期: 2012
卷: 68, 期:38, 页:7763-7767
部门归属: [Yang, Xian-Wen] Chinese Acad Sci, S China Sea Inst Oceanol, Key Lab Marine Bioresources Sustainable Utilizat, Guangzhou 510301, Guangdong, Peoples R China; [Li, Yong-Li; Zhang, Shou-De; Jin, Hui-Zi; Zhang, Wei-Dong] Shanghai Jiao Tong Univ, Sch Pharm, Shanghai 200240, Peoples R China; [Tian, Jun-Mian; Shen, Yun-Heng; Zhang, Wei-Dong] Mil Med Coll 2, Sch Pharm, Shanghai 200433, Peoples R China; [Yang, Xian-Wen] Luxembourg Publ Res Ctr Hlth CRP SANTE, L-1526 Luxembourg, Luxembourg; [Zhang, Shou-De; Li, Hong-Lin] E China Univ Sci & Technol, Sch Pharm, Shanghai 200237, Peoples R China
项目归属: LMB
摘要: Abiestetranes A (1) and B (2), two unique tetraterpenes formed by Diels-Alder cycloaddition between a lanostane triterpenoid and a monoterpenoid, were isolated from Abies fabri. Their structures were elucidated by extensive analysis of NMR data. The electronic circular dichroism was utilized to assign the absolute configuration of 1. Compounds 1 and 2 showed significant cytotoxic activities against ZR-75-30 tumor cell with IC50 values of 6.26 and 1.63 mu g/mL, respectively. (C) 2012 Elsevier Ltd. All rights reserved.
语种: 英语
WOS记录号: WOS:000308051600003
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.scsio.ac.cn/handle/344004/9800
Appears in Collections:中科院海洋生物资源可持续利用重点实验室_期刊论文

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Recommended Citation:
Li, YL; Zhang, SD; Jin, HZ; Tian, JM; Shen, YH; Yang, XW; Li, HL; Zhang, WD.Abiestetranes A and B, two unique tetraterpenes from Abies fabri,TETRAHEDRON,2012,68(38):7763-7767
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