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学科主题: Plant Sciences; Chemistry, Medicinal; Pharmacology & Pharmacy
题名: New Monoterpenes, Diterpenes, and Lignans from Abies recurvata
作者: Li, YL ; Zhang, JG ; Yu, P ; Ke, BL ; Ye, J ; Yang, XW ; Jin, HZ ; Zhang, WD
通讯作者: xianwen.yang@crp-sante.lu ; wdzhangy@hotmail.com
关键词: Abies recurvate ; Pinaceae ; monoterpenes ; diterpenes ; lignin ; nitric oxide ; lipopolysaccharide
刊名: PLANTA MEDICA
发表日期: 2012
卷: 78, 期:14, 页:1574-1578
部门归属: [Yang, Xian-Wen] Luxembourg Publ Res Ctr Hlth CRP SANTE, Dept Oncol, Lab Mol & Cellular Oncol, L-1526 Luxembourg, Luxembourg; [Li, Yong-Li; Jin, Hui-Zi; Zhang, Wei-Dong] Shanghai Jiao Tong Univ, Sch Pharm, Shanghai 200030, Peoples R China; [Zhang, Ji-Gang; Yu, Ping; Ke, Bei-Lei; Ye, Ji; Zhang, Wei-Dong] Mil Med Coll 2, Sch Pharm, Shanghai, Peoples R China; [Yang, Xian-Wen] Chinese Acad Sci, Key Lab Marine Bioresources Sustainable Utilizat, Guangdong Key Lab Marine Mat Med, Guangzhou, Guangdong, Peoples R China; [Yang, Xian-Wen] Chinese Acad Sci, S China Sea Inst Oceanol, RNAM Ctr Marine Microbiol, Guangzhou, Guangdong, Peoples R China
项目归属: LMB
摘要: From the aerial part of Abies recurvata, 62 miscellaneous chemical constituents were isolated including 6 new and 56 known ones. The new compounds comprised three monoterpenes, two diterpenes, and one lignan. Their chemical structures were characterized on the basis of various spectroscopic techniques. Dihydrodehydrodiconiferyl alcohol (35) showed the strongest inhibitory effects against lipopolysaccharide-induced nitric oxide production in RAW 264.7 cells with an IC50 value of 66.4 mu M.
语种: 英语
WOS记录号: WOS:000309521800011
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.scsio.ac.cn/handle/344004/9810
Appears in Collections:中科院海洋生物资源可持续利用重点实验室_期刊论文

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Li, YL; Zhang, JG; Yu, P; Ke, BL; Ye, J; Yang, XW; Jin, HZ; Zhang, WD.New Monoterpenes, Diterpenes, and Lignans from Abies recurvata,PLANTA MEDICA,2012,78(14):1574-1578
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