SCSIO OpenIR  > 中科院海洋生物资源可持续利用重点实验室
New Cembrane Diterpenoids from a Hainan Soft Coral Sinularia sp.
Yang, B; Zhou, XF; Huang, H; Yang, XW; Liu, J; Lin, XP; Li, XB; Peng, Y; Liu, YH; bingo525@163.com; xfzhou@scsio.ac.cn; huanghui@scsio.ac.cn; xwyang@scsio.ac.cn; ljuan2010@qq.com; xiupinglin@hotmail.com; lixiubao@scsio.ac.cn; py00_2006@126.com; yonghongliu@scsio.ac.cn
2012
Source PublicationMARINE DRUGS
ISSN1660-3397
Volume10Issue:9Pages:2023-2032
AbstractFive new cembrane diterpenoids, named sinuflexibilins A-E (1-5), along with nine other known diterpenoids (6-14), have been isolated from the organic extract of a Hainan soft coral Sinularia sp. Their structures were determined on the basis of extensive spectroscopic analyses and by comparison of their spectral data with those of related metabolites. Compound 13, flexibilide, exhibited significant inhibitory activity of NF-kappa B activation using the cell-based HEK293 NF-kappa B luciferase reporter gene assay.
Department[Yang, Bin; Zhou, Xuefeng; Huang, Hui; Yang, Xian-Wen; Liu, Juan; Lin, Xiuping; Li, Xiubao; Peng, Yan; Liu, Yonghong] Chinese Acad Sci, S China Sea Inst Oceanol, Key Lab Marine Bioresources Sustainable Utilizat, Guangzhou 510301, Guangdong, Peoples R China; [Yang, Bin; Zhou, Xuefeng; Yang, Xian-Wen; Liu, Juan; Lin, Xiuping; Peng, Yan; Liu, Yonghong] Chinese Acad Sci, S China Sea Inst Oceanol, RNAM Ctr Marine Microbiol, Guangdong Key Lab Marine Mat Med, Guangzhou 510301, Guangdong, Peoples R China
KeywordSinularia Sp. Cembrane Diterpenoids Nf-kappa b Inhibitor
Subject AreaChemistry, Medicinal
Language英语
Funding ProjectLMB
WOS IDWOS:000309270800008
Citation statistics
Cited Times:15[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Identifierhttp://ir.scsio.ac.cn/handle/344004/9816
Collection中科院海洋生物资源可持续利用重点实验室
Corresponding Authorbingo525@163.com; xfzhou@scsio.ac.cn; huanghui@scsio.ac.cn; xwyang@scsio.ac.cn; ljuan2010@qq.com; xiupinglin@hotmail.com; lixiubao@scsio.ac.cn; py00_2006@126.com; yonghongliu@scsio.ac.cn
Recommended Citation
GB/T 7714
Yang, B,Zhou, XF,Huang, H,et al. New Cembrane Diterpenoids from a Hainan Soft Coral Sinularia sp.[J]. MARINE DRUGS,2012,10(9):2023-2032.
APA Yang, B.,Zhou, XF.,Huang, H.,Yang, XW.,Liu, J.,...&yonghongliu@scsio.ac.cn.(2012).New Cembrane Diterpenoids from a Hainan Soft Coral Sinularia sp..MARINE DRUGS,10(9),2023-2032.
MLA Yang, B,et al."New Cembrane Diterpenoids from a Hainan Soft Coral Sinularia sp.".MARINE DRUGS 10.9(2012):2023-2032.
Files in This Item:
File Name/Size DocType Version Access License
marinedrugs-10-02023(598KB) 开放获取--Application Full Text
Related Services
Recommend this item
Bookmark
Usage statistics
Export to Endnote
Terms of Use
No data!
Social Bookmark/Share
All comments (0)
No comment.
 

Items in the repository are protected by copyright, with all rights reserved, unless otherwise indicated.