New Cembrane Diterpenoids from a Hainan Soft Coral Sinularia sp.
Yang, B; Zhou, XF; Huang, H; Yang, XW; Liu, J; Lin, XP; Li, XB; Peng, Y; Liu, YH; bingo525@163.com; xfzhou@scsio.ac.cn; huanghui@scsio.ac.cn; xwyang@scsio.ac.cn; ljuan2010@qq.com; xiupinglin@hotmail.com; lixiubao@scsio.ac.cn; py00_2006@126.com; yonghongliu@scsio.ac.cn
2012
发表期刊MARINE DRUGS
ISSN1660-3397
卷号10期号:9页码:2023-2032
摘要Five new cembrane diterpenoids, named sinuflexibilins A-E (1-5), along with nine other known diterpenoids (6-14), have been isolated from the organic extract of a Hainan soft coral Sinularia sp. Their structures were determined on the basis of extensive spectroscopic analyses and by comparison of their spectral data with those of related metabolites. Compound 13, flexibilide, exhibited significant inhibitory activity of NF-kappa B activation using the cell-based HEK293 NF-kappa B luciferase reporter gene assay.
部门归属[Yang, Bin; Zhou, Xuefeng; Huang, Hui; Yang, Xian-Wen; Liu, Juan; Lin, Xiuping; Li, Xiubao; Peng, Yan; Liu, Yonghong] Chinese Acad Sci, S China Sea Inst Oceanol, Key Lab Marine Bioresources Sustainable Utilizat, Guangzhou 510301, Guangdong, Peoples R China; [Yang, Bin; Zhou, Xuefeng; Yang, Xian-Wen; Liu, Juan; Lin, Xiuping; Peng, Yan; Liu, Yonghong] Chinese Acad Sci, S China Sea Inst Oceanol, RNAM Ctr Marine Microbiol, Guangdong Key Lab Marine Mat Med, Guangzhou 510301, Guangdong, Peoples R China
关键词Sinularia Sp. Cembrane Diterpenoids Nf-kappa b Inhibitor
学科领域Chemistry, Medicinal
语种英语
资助项目LMB
WOS记录号WOS:000309270800008
引用统计
被引频次:15[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.scsio.ac.cn/handle/344004/9816
专题中科院海洋生物资源可持续利用重点实验室
通讯作者bingo525@163.com; xfzhou@scsio.ac.cn; huanghui@scsio.ac.cn; xwyang@scsio.ac.cn; ljuan2010@qq.com; xiupinglin@hotmail.com; lixiubao@scsio.ac.cn; py00_2006@126.com; yonghongliu@scsio.ac.cn
推荐引用方式
GB/T 7714
Yang, B,Zhou, XF,Huang, H,et al. New Cembrane Diterpenoids from a Hainan Soft Coral Sinularia sp.[J]. MARINE DRUGS,2012,10(9):2023-2032.
APA Yang, B.,Zhou, XF.,Huang, H.,Yang, XW.,Liu, J.,...&yonghongliu@scsio.ac.cn.(2012).New Cembrane Diterpenoids from a Hainan Soft Coral Sinularia sp..MARINE DRUGS,10(9),2023-2032.
MLA Yang, B,et al."New Cembrane Diterpenoids from a Hainan Soft Coral Sinularia sp.".MARINE DRUGS 10.9(2012):2023-2032.
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