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学科主题: Acoustics; Chemistry, Multidisciplinary
题名: Ultrasound-assisted extraction of oleanolic acid and ursolic acid from Ligustrum lucidum Ait
作者: Xia, EQ ; Yu, YY ; Xu, XR ; Deng, GF ; Guo, YJ ; Li, HB
通讯作者: lihuabin@mail.sysu.edu.cn
关键词: Ultrasound ; Extraction ; Oleanolic acid ; Ursolic acid ; Ligustrum lucidum
刊名: ULTRASONICS SONOCHEMISTRY
发表日期: 2012
卷: 19, 期:4, 页:772-776
部门归属: [Xia, En-Qin; Yu, Ying-Ying; Deng, Gui-Fang; Guo, Ya-Jun; Li, Hua-Bin] Sun Yat Sen Univ, Guangdong Prov Key Lab Food Nutr & Hlth, Sch Publ Hlth, Guangzhou 510080, Guangdong, Peoples R China; [Xu, Xiang-Rong] Chinese Acad Sci, Key Lab Marine Bioresources Sustainable Utilizat, S China Sea Inst Oceanol, Guangzhou 510301, Guangdong, Peoples R China
项目归属: LMB
摘要: Oleanolic acid and ursolic acid are the main bioactive compounds in fruit of Ligustrum lucidum Ait, which possess anti-inflammatory, antioxidative, antiprotozoal, antimutagenic and anticancer properties. In this study, the ultrasound-assisted extraction of oleanolic acid and ursolic acid from L lucidum Ait was investigated with HPLC-photodiode array detection. Effects of several experimental parameters, such as type and concentration of extraction solvent, ratio of liquid to material, extraction temperature and extraction time, on extraction efficiencies of oleanolic acid and ursolic acid from L. lucidum were evaluated. The influence of experimental parameters on extraction efficiency of ursolic acid was more significant than that of oleanolic acid. The optimal extraction conditions were 95% ethanol, the ratio of material to liquid at 1:20, and extraction for 10 min at 40 degrees C under ultrasonic irradiation. Under the optimal conditions, the yields of oleanolic acid and ursolic acid were 6.3 +/- 0.25 and 9.8 +/- 0.30 mg/g. respectively. The results indicated that the ultrasound-assisted extraction is a very useful method for the extraction of oleanolic acid and ursolic acid from L lucidum. (C) 2011 Elsevier B.V. All rights reserved.
语种: 英语
WOS记录号: WOS:000302044000011
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.scsio.ac.cn/handle/344004/9876
Appears in Collections:中科院海洋生物资源可持续利用重点实验室_期刊论文

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Xia, EQ; Yu, YY; Xu, XR; Deng, GF; Guo, YJ; Li, HB.Ultrasound-assisted extraction of oleanolic acid and ursolic acid from Ligustrum lucidum Ait,ULTRASONICS SONOCHEMISTRY,2012,19(4):772-776
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