Abieseconordines A and B, Two Novel Norditerpenoids with a 18-Nor-5,10:9,10-disecoabietane Skeleton from Abies forrestii
Yu, P; Zhang, SD; Li, YL; Yang, XW; Zeng, HW; Li, HL; Zhang, WD; xwyang@scsio.ac.cn; wdzhangy@hotmail.com
2012
发表期刊HELVETICA CHIMICA ACTA
ISSN0018-019X
卷号95期号:3页码:415-422
摘要A systematic phytochemical investigation on Abies forrestii afforded two new and 20 known compounds. Abieseconordines A and B (1 and 2) are the first two examples of norditerpenes with a novel 18-nor-5,10?:?9,10-disecoabietane skeleton. Their structures were established mainly by analysis of 1D- and 2D-NMR spectroscopic data. In addition, electronic circular-dichroism calculations and molecular-orbital analysis were utilized to confirm the absolute configuration of 1. Both compounds exhibited a potent effect in a bioassay inhibiting LPS-stimulated NO production in RAW264.7 macrophages.
部门归属[Yang, Xian-Wen] Chinese Acad Sci, Guangdong Key Lab Marine Mat Med, Key Lab Marine Bioresources Sustainable Utilizat, S China Sea Inst Oceanol, Guangzhou 510301, Guangdong, Peoples R China; [Yang, Xian-Wen] Chinese Acad Sci, S China Sea Inst Oceanol, RNAM Ctr Marine Microbes, Guangzhou 510301, Guangdong, Peoples R China; [Yu, Ping; Zhang, Wei-Dong] Mil Med Coll 2, Sch Pharm, Dept Nat Prod Chem, Shanghai 200433, Peoples R China; [Zhang, Shou-De; Li, Yong-Li; Zeng, Hua-Wu; Zhang, Wei-Dong] Shanghai Jiao Tong Univ, Sch Pharm, Shanghai 200240, Peoples R China; [Li, Hong-Lin] E China Univ Sci & Technol, Sch Pharm, Shanghai Key Lab Chem Biol, Shanghai 200237, Peoples R China
关键词Abies Forrestii Abieseconordines a And b Electronic Circular Dichroism (Ecd) Ditepenoids Nitric Oxide Density-functional Theory (Dft)
学科领域Chemistry, Multidisciplinary
语种英语
资助项目LMB
WOS记录号WOS:000301574200004
引用统计
文献类型期刊论文
条目标识符http://ir.scsio.ac.cn/handle/344004/9962
专题中科院海洋生物资源可持续利用重点实验室
通讯作者xwyang@scsio.ac.cn; wdzhangy@hotmail.com
推荐引用方式
GB/T 7714
Yu, P,Zhang, SD,Li, YL,et al. Abieseconordines A and B, Two Novel Norditerpenoids with a 18-Nor-5,10:9,10-disecoabietane Skeleton from Abies forrestii[J]. HELVETICA CHIMICA ACTA,2012,95(3):415-422.
APA Yu, P.,Zhang, SD.,Li, YL.,Yang, XW.,Zeng, HW.,...&wdzhangy@hotmail.com.(2012).Abieseconordines A and B, Two Novel Norditerpenoids with a 18-Nor-5,10:9,10-disecoabietane Skeleton from Abies forrestii.HELVETICA CHIMICA ACTA,95(3),415-422.
MLA Yu, P,et al."Abieseconordines A and B, Two Novel Norditerpenoids with a 18-Nor-5,10:9,10-disecoabietane Skeleton from Abies forrestii".HELVETICA CHIMICA ACTA 95.3(2012):415-422.
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