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Repurposing a bacterial prolidase for organophosphorus hydrolysis: Reshaped catalytic cavity switches substrate selectivity 期刊论文
BIOTECHNOLOGY AND BIOENGINEERING, 2020, 卷号: 117, 期号: 9, 页码: 2694, 2702
Authors:  Yang, Jian;  Xiao, Yun-Zhu;  Li, Ru;  Liu, Yu;  Long, Li-Juan
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active-site reshaping  catalytic selectivity  enzyme promiscuity  protein engineering  substrate repositioning  
A high density genetic map by whole-genome resequencing for QTL fine-mapping and dissecting candidate genes for growth or sex traits in the pearl oyster (Pinctada fucata martensii) 期刊论文
AQUACULTURE, 2020, 卷号: 519, 页码: 734839
Authors:  Liu, Huiru;  Zhang, Hua;  Pan, Xiaolan;  Xu, Meng;  Huang, Jing;  He, Maoxian
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Pinctada fucata martensii  Genetic linkage map  Whole-genome resequencing  Quantitative trait loci  Transcriptomic analysis  
On-PKS Baeyer-Villiger-Type O-Atom Insertion Catalyzed by Luciferase-Like Monooxygenase OvmO during Olimycin Biosynthesis 期刊论文
ORGANIC LETTERS, 2020, 卷号: 22, 期号: 5, 页码: 1780, 1784
Authors:  Zhang, Chunyan;  Zhang, Huaran;  Ju, Jianhua
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Dietary separation between co-occurring copepods in a food-limited tropical coral reef of the Sanya Bay 期刊论文
ACTA OCEANOLOGICA SINICA, 2020, 卷号: 39, 期号: 4, 页码: 65, 72
Authors:  Hu, Simin;  Li, Tao;  Liu, Sheng;  Huang, Hui
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copepod  food partitioning  Sanya Bay  coral reef ecosystem  
Understand the Specific Regio- and Enantioselectivity of Fluostatin Conjugation in the Post-Biosynthesis 期刊论文
BIOMOLECULES, 2020, 卷号: 10, 期号: 6, 页码: 815
Authors:  Wang, Yuanqi;  Zhang, Changsheng;  Zhao, Yi-Lei;  Zhao, Rosalinda;  Houk, Kendall N.
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fluostatin  conjugation  regioselectivity  stereoselectivity  pi-pi stacking interaction  
Scorpion Toxins: Positive Selection at a Distal Site Modulates Functional Evolution at a Bioactive Site 期刊论文
MOLECULAR BIOLOGY AND EVOLUTION, 2019, 卷号: 36, 期号: 2, 页码: 365, 375
Authors:  Zhu, Limei;  Gao, Bin;  Yuan, Shouli;  Zhu, Shunyi
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bioactive site  distal site  toxin-channel interface  long-range communication  positive selection  
Chemical Diversification Based on Substrate Promiscuity of a Standalone Adenylation Domain in a Reconstituted NRPS System 期刊论文
ACS CHEMICAL BIOLOGY, 2019, 卷号: 14, 期号: 2, 页码: 256, 265
Authors:  Zhu, Mengyi;  Wang, Lijuan;  He, Jing
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Cytochrome P450 oxidase SlgO1 catalyzes the biotransformation of tirandamycin C to a new tirandamycin derivative 期刊论文
3 BIOTECH, 2019, 卷号: 9, 期号: 3, 页码: 71
Authors:  Mo, Xuhua;  Gui, Chun;  Yang, Song
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Tirandamycins  Streptolydigin  Cytochrome P450 oxidase SlgO1  Combinatorial biosynthesis  
南海珊瑚礁植食性鱼类典型功能群摄食生态研究 学位论文
博士: 南海海洋研究所, 2019
Authors:  林先智
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高通量测序,生境变化,功能冗余,摄食分析,珊瑚礁生态系统  
海洋真菌细菌共生体F190/B001代谢产物及Aborycin生物合成研究 学位论文
博士: 南海海洋研究所, 2019
Authors:  邵明伟
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海洋微生物,真菌-细菌共生体,抗感染化合物,Aborycin,异源表达